上海埃飞科技
Worldwide Technology(S. H)产品展示
Micareo-自动化细胞分选分析影像平台
许多液体活检解决方案仅针对样本分析过程的一部分,不能满足药物开发、临床和研究实验室的需求。MiSelect R 系统可以放置在任何地方,任何人只需接受几个小时的培训即可使用。它提供了对医学研究人员和药物开发人员进行开创性单细胞下游分析所需的原材料(稀有细胞、CTC、免疫细胞)的一致访问。
MiSelect R 实现了 90% 的细胞回收率,而变异小于 10%。最重要的是,用户可以自信地期待这些结果,而不受操作员经验水平的影响。
此外,这一重要的结果不应该花费数天甚至数周才能从中心实验室返回。只需 10 分钟的手动准备时间即可处理两个全血样本,并在几个小时内完成稀有靶细胞的自动成像,这一切都在您自己的实验室中完成。
这种多合一设备包含从细胞选择到抗体标记再到荧光成像的全自动过程,可确保最大限度地减少样品损失并重现结果。彩神iv争霸温和的过程和集成的仪器可以始终如一地访问分离的稀有活细胞,例如 CTC 和免疫细胞。MiSelect R 足够紧凑,可以放在工作站的角落,非常适合任何实验室,无论大小。
应用领域
循环肿瘤细胞
监测患者血液中 CTC 水平和类型的能力提供了丰富的信息,这些信息与所有其他当前诊断信息互补且不同。循环肿瘤细胞的分离和纯化以及随后对其生化变化的分析,将大大增强彩神iv争霸对癌症转移的理解,以及对实验药物/治疗的评估。
CTC计数有许多潜在的应用
包括监测药物反应/耐药性、预测癌症患者的临床结果或早期检测潜在的转移。然而,癌症患者的 CTC 计数可能非常低。10 毫升的血液可能含有数十亿个红细胞、数百万个白细胞和只有一个 CTC。与许多 CTC 计数技术不同,MiSelect 保留了分离细胞的完整性,提供了对完整范围的基因组和细胞信息的访问。
稀有免疫细胞
监测治疗效果越来越困难。在肿瘤细胞中没有发现许多检查点阻断剂,但发现抑制剂作用于免疫细胞,例如细胞毒性 CD8(+) T 细胞。分析免疫细胞可能会提供有关细胞反应或对实验治疗的抵抗力的更完整信息。
Products Introduction
Unlocking the secrets of rarecells
MiCareo is pushing beyond thelimits of current liquid biopsy technologies by providing high purity isolatedlive rare cells and automated multiplexed fluorescence imaging. We are buildingtechnologies to accelerate the way pharmaceutical companies monitor drugresponse & screen for drug effectiveness, and giving researchers the toolsto find new correlations in biomarker expression using fully quantitativevisual subtyping of each cell.
Advantages
The MiSelect R achieves 90% cellrecovery with less than 10% variation.Best of all, users can confidently expect these results independent ofoperator experience level.
Furthermore, results thisimportant should not take days, or even weeks, to get back from a central lab.Process two samples of whole blood with only 10 minutes of hands on prep, andcomplete the automated imaging of rare target cells within a few hours, all inyour own lab.
This all-in-one device houses afully automated process from cell selection, to antibody labeling, tofluorescence imaging, which ensures that sample loss is minimized andresults are reproducible. Our gentle process and integrated instrument giveconsistent access to isolated live rare cells such as CTCs, and immune cells.
The MiSelect R is compactenough to fit on the corner of your workstation, making it a perfect fit forany lab, big or small.
Applications
Circulating Tumor Cells
The ability to monitor the level and type ofCTCs in a patient's blood provides rich information that is complementary anddistinct from all other current diagnostic information. The isolation andpurification of circulating tumor cells and the subsequent profiling of theirbiochemical changes, will greatly enhance both our understanding of cancer metastases,and in the assessment of experimental drugs/treatments.
Power of Enumeration
CTC enumeration has numerous potentialapplications include monitoring drug response/resistance, predicting theclinical outcome of cancer patients, or detecting potential metastasis early.However, CTC counts in cancer patients could be are incredibly low. 10 mLof blood may contain billions of RBCs, millions of leukocytes, and onlyone CTC.
Although detection, isolation, and analysisof CTCs has posed a challenge in the medical field, MiCareohas consistently achieved a 90% recovery efficiency with less than10% variation lab tests.
And unlike many CTC enumeration technologies,MiSelect preserves the integrity of isolated cells, affording accessto the complete range of genomic as well as cellular information.
Rare Immune Cells
Monitoring treatment efficacy is increasinglydifficult. Many checkpoint blockades are not found in tumor cells,but inhibitors are instead found acting upon immune cells suchas cytotoxic CD8(+) T cells. Profiling immune cells may give more completeinformation as to cell response or resistance to experimentaltreatments.
因用于机器人各方面应用且与大多数机器人类型兼容,AutoCal系统可以检测出机器人自身构造和工具中心点(TCP)的 突然改变或偏离,并且该系统无需人为干涉就自动地更正这些误差。
AutoCal系统-Dynalog的先进水平校准技术,Dynalog是机器人单元标定技术的世界领导者。它的主流产品DynaCal 系统,被应用于离线的机器人单元校准,并作为最精确的和技术先进的机器人校准程序为许多机器人制造商和终端使用者所接受。AutoCal 系统将已证实的DynaCal校准技术结合到一个在线的全自动系统中,该系统专为程序控制和复原而设计的,价格低廉。
AutoCal系统提供在线的机器人校准方案,旨在快速和自动地保证机械设备的工作性能。因用于机器人各方面应用且与大多数机器人类型兼容,AutoCal系统可以检测出机器人自身构造和工具中心点(TCP)的 突然改变或偏离,并且该系统无需人为干涉就自动地更正这些误差。这意味着不用猜测哪里会出错,不用浪费宝贵时间在机器人程序重复校准上,产品品质无任何损失。
AutoCal系统-Dynalog的先进水平校准技术,Dynalog是机器人单元标定技术的世界领导者。它的主流产品DynaCal 系统,被应用于离线的机器人单元校准,并作为最精确的和技术先进的机器人校准程序为许多机器人制造商和终端使用者所接受。AutoCal 系统将已证实的DynaCal校准技术结合到一个在线的全自动系统中,该系统专为程序控制和复原而设计的,价格低廉。